SCHEMBL533336

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL533202	0.98	TLR8 (0.43)	TLR8ESR1ADRA2AADORA3TACR2
	SCHEMBL533147	0.95	SKP2 (0.45)	TLR8SKP2ALDH1A1TP53HSD17B10
	SCHEMBL533281	0.88	CNR1 (0.39)	SKP2ADRA2ATP53HSD17B10ADRA2B
	SCHEMBL5536300	0.86	TLR8 (0.43)	TLR8ESR1ADRA2AADORA3TACR2
	SCHEMBL6563401	0.74	BDKRB2 (0.55)	TLR8ESR1ADRA2AADORA3TACR2
	SCHEMBL533265	0.74	CA12 (0.48)	ALDH1A1CYP3A4
	SCHEMBL534319	0.74	NR5A1 (0.45)	TP53
	SCHEMBL533425	0.73	GABRA1 (0.40)	ESR1ADORA3SLC6A2SLC6A3KDM4E
	SCHEMBL20126467	0.73	ESR1 (0.42)	TLR8ESR1ADRA2AADORA3TACR2
	SCHEMBL533900	0.73	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.