SCHEMBL533425

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL533255	0.80	CYP1A2 (0.44)	MEN1KMT2AMAPTLMNAAKR1C3
	SCHEMBL533281	0.77	CNR1 (0.39)	ALOX5TP53ADRA2BCNR1HRH1
	SCHEMBL533336	0.73	TLR8 (0.42)	HTR2AHTR2CPTGS2PTGS1LMNA
	SCHEMBL27718663	0.73	POLB (0.36)	POLBMAPTPTGS1LMNAAKR1C3
	SCHEMBL533030	0.73	RAB9A (0.42)	MEN1KMT2AMAPTPTGS1LMNA
	SCHEMBL28292686	0.72	HTR2A (0.57)	GABRA1GABRB2HTR2AHTR2BHTR2C
	SCHEMBL533900	0.72	—	—
	SCHEMBL533531	0.72	XDH (0.40)	ABL1POLBMAPTLMNACYP2C9
	SCHEMBL12853146	0.71	GABRA1 (0.42)	GABRA1GABRB2HTR2AHTR2BHTR2C
	SCHEMBL8221541	0.70	GABRA1 (0.41)	GABRA1GABRB2HTR2AHTR2BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.