Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.46 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28827396 | 0.85 | CYP1A1 (0.48) | CYP3A4CYP1A2CYP2C9CYP2B6CYP1A1 | |
| SCHEMBL323109 | 0.84 | DYRK1A (0.49) | DYRK1ACLK4CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL28480166 | 0.83 | CYP1A2 (0.53) | CYP3A4CYP1A2CYP2C9CYP2B6CYP2D6 | |
| SCHEMBL6131987 | 0.82 | MAOB (0.44) | HDAC8SMN1; SMN2GAAMAOBMAPT | |
| SCHEMBL6963144 | 0.81 | MAPT (0.47) | CYP3A4RAB9ASMN1; SMN2TDP1TP53 | |
| SCHEMBL7465925 | 0.81 | CYP1A2 (0.46) | DYRK1ACLK4CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3737126 | 0.81 | RXRA (0.48) | CYP3A4SMN1; SMN2TP53GAAMAOB | |
| SCHEMBL592654 | 0.79 | CA4 (0.44) | CLK4HDAC4HDAC8NFKB1RAB9A | |
| SCHEMBL7832248 | 0.79 | ACHE (0.53) | DYRK1ACLK4CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3729005 | 0.79 | KDM4E (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| CN-1159289-C | C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cystenine proteases | ������˹ҩƷ��˾ | 2004-07-28 | — | — | CN | claimed |
| US-5223640-A | Regioselectively silylcarbonylating arylacetylene, oxidizing, desilylating, hydrogenating | HOECHST CELANESE CORPORATION (US) | 1993-06-29 | — | — | US | claimed |
| WO-2019028104-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ALPHALA CO., LTD. (TW) | 2019-02-07 | — | — | WO | disclosed |
| CN-104387303-B | The asymmetric over cure compound of aryl-aryl, aryl-alkyl, alkyl-alkyl and synthetic method thereof | 华东师范大学 | 2016-06-29 | — | — | CN | disclosed |
| CN-104140448-A | Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2014-11-12 | — | — | CN | disclosed |
| CN-104140442-A | Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2014-11-12 | — | — | CN | disclosed |
| CN-104140441-A | Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2014-11-12 | — | — | CN | disclosed |
| CN-101160345-B | Method for producing aromatic polymer | SUMITOMO CO LTD | 2013-01-16 | — | — | CN | disclosed |
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| CN-101611071-B | Method for production of block copolymer | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-101160345-A | Method for producing aromatic polymer | SUMITOMO CHEMICAL CO (JP) | 2008-04-09 | — | — | CN | disclosed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| CN-1628122-A | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HOKKO CHEM IND CO (JP) | 2005-06-15 | — | — | CN | disclosed |
| EP-0976748-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147100-A | ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0976748-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0581540-B1 | Silicone release composition | GEN ELECTRIC (US) | 1997-06-04 | — | — | EP | disclosed |
| US-5190958-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |