Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3729005 | 0.88 | KDM4E (0.47) | MAPTKDM4EGAATP53SMN1; SMN2 | |
| SCHEMBL4218764 | 0.84 | CYP1A2 (0.35) | MAPTKDM4EGAARXRARXRB | |
| SCHEMBL533385 | 0.81 | DYRK1A (0.47) | MAPTGAATDP1TP53CYP3A4 | |
| SCHEMBL3735038 | 0.81 | NQO1 (0.50) | MAPTKDM4EGAATDP1TP53 | |
| SCHEMBL8074390 | 0.81 | MAOB (0.51) | — | |
| SCHEMBL6883783 | 0.80 | SIRT1 (0.40) | MAPTKDM4EGAAFGFR1SMN1; SMN2 | |
| SCHEMBL3197832 | 0.80 | KDM4E (0.43) | MAPTKDM4EGAARXRARXRB | |
| SCHEMBL18239968 | 0.80 | MAPT (0.43) | MAPTKDM4EGAARXRARXRB | |
| SCHEMBL6136820 | 0.80 | DYRK1A (0.44) | MAPTKDM4EGAARXRARXRB | |
| SCHEMBL29426410 | 0.78 | RXRA (0.66) | MAPTKDM4EGAARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104140441-A | Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2014-11-12 | — | — | CN | disclosed |
| CN-104140442-A | Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2014-11-12 | — | — | CN | disclosed |
| CN-104140448-A | Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device | OCEANS KING LIGHTING SCIENCE | 2014-11-12 | — | — | CN | disclosed |
| EP-0976748-B1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147100-A | ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0976748-A1 | PYRROLIDINE DERIVATIVES HAVING PHOSPHOLIPASE A2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |