Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | FPR2 | P25090 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761293 | 0.85 | CNR1 (0.48) | CNR1FPR2HTTLMNASMN1; SMN2 | |
| SCHEMBL5764893 | 0.84 | CNR1 (0.47) | CNR1FPR2HTTLMNASMN1; SMN2 | |
| SCHEMBL5759633 | 0.84 | CNR1 (0.46) | CNR1FPR2HTTLMNASMN1; SMN2 | |
| SCHEMBL6622638 | 0.83 | SCN9A (0.37) | CNR1LMNAKMT2A | |
| SCHEMBL6623481 | 0.80 | MAPT (0.36) | CNR1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6620915 | 0.80 | CYP3A4 (0.43) | FPR2LMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL6620453 | 0.80 | SCN9A (0.35) | LMNASMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL6661476 | 0.77 | FPR1 (0.43) | CNR1FPR2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6621560 | 0.77 | CYP1A2 (0.43) | FPR2LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5337976 | 0.77 | FPR1 (0.43) | CNR1FPR2LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487435-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | Novartis AG (CH) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003077907-A1 | AZETIDINE DERIVATIVES AS CCR-3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2003-09-25 | — | — | WO | disclosed |