SCHEMBL5334645

SCHEMBL5334645

C=CC(O)c1ccccc1P

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594286 0.84 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL15388937 0.77 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL5614870 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL526123 0.76 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL9555419 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL387118 0.76 GABRA1 (0.48) ALDH1A1TSHR
SCHEMBL9815785 0.76 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL2068749 0.74 IDO1 (0.36) ALDH1A1TSHR
SCHEMBL5614611 0.74 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL8439675 0.74 ALDH1A1 (0.32) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007057690-A1 DESYMMETRISATION PROCESS FOR THE PRODUCTION OF CYCLIC PHOSPHINES USED AS LIGANDS IN ENANTIOSELECTIVE SYNTHESIS CATALYSTS ISIS INNOVATION LIMITED (GB) 2007-05-24 WO disclosed