Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10294635 | 0.82 | POLB (0.58) | HSD17B10POLBNR4A1RAB9ATSHR | |
| SCHEMBL18518257 | 0.80 | POLB (0.55) | HSD17B10POLBNR4A1RAB9ATSHR | |
| SCHEMBL19890916 | 0.78 | MAOA (0.49) | MEN1KMT2AALDH1A1MTNR1AMTNR1B | |
| SCHEMBL14544620 | 0.76 | RAB9A (0.51) | HSD17B10POLBNR4A1RAB9ATSHR | |
| SCHEMBL17324145 | 0.75 | ALDH1A1 (0.61) | HSD17B10POLBNR4A1RAB9AMEN1 | |
| SCHEMBL13836493 | 0.75 | ALDH1A1 (0.61) | HSD17B10POLBNR4A1RAB9AMEN1 | |
| SCHEMBL5316260 | 0.74 | MAOA (0.42) | HSD17B10TSHRALDH1A1MTNR1AMTNR1B | |
| SCHEMBL5208634 | 0.74 | MAPT (0.70) | HSD17B10POLBRAB9AMEN1KMT2A | |
| SCHEMBL21415471 | 0.72 | ALDH1A1 (0.58) | HSD17B10POLBNR4A1RAB9AMEN1 | |
| SCHEMBL4219569 | 0.72 | ALDH1A1 (0.58) | HSD17B10POLBNR4A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064869-A2 | CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES | YALE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |