Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502936 | 1.00 | LIPE (0.41) | LIPEP2RX3KCNH2SCN5ASCN9A | |
| SCHEMBL4508563 | 0.90 | SCN9A (0.36) | LIPESCN9A | |
| SCHEMBL4523713 | 0.89 | LIPE (0.44) | LIPEP2RX3KCNH2SCN5ASCN9A | |
| SCHEMBL4240879 | 0.88 | LIPE (0.40) | LIPEP2RX3KCNH2SCN5ASCN9A | |
| SCHEMBL13763253 | 0.85 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL5336561 | 0.84 | RAB9A (0.51) | POLBCHRNB4CHRNA3 | |
| SCHEMBL4506024 | 0.84 | RAB9A (0.51) | POLBCHRNB4CHRNA3 | |
| SCHEMBL5333541 | 0.83 | PDE10A (0.41) | — | |
| SCHEMBL4518401 | 0.83 | PDE10A (0.41) | — | |
| SCHEMBL13854944 | 0.81 | LIPE (0.42) | LIPEP2RX3KCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |