SCHEMBL5333541

SCHEMBL5333541

CCN1C(=O)OCC1Cc1ccc(Oc2ccc(Nc3ccccn3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4518401 1.00 PDE10A (0.41) PDE10A
SCHEMBL5331086 0.89 MET (0.39)
SCHEMBL4509997 0.89 MET (0.39)
SCHEMBL4511519 0.88 PDE10A (0.42) PDE10A
SCHEMBL4506585 0.88 PDE10A (0.42) PDE10A
SCHEMBL4241402 0.87 PDE10A (0.42) PDE10A
SCHEMBL13763253 0.83 P2RX3 (0.34)
SCHEMBL5336561 0.83 RAB9A (0.51)
SCHEMBL4502936 0.83 LIPE (0.41)
SCHEMBL4506024 0.83 RAB9A (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007029062-A2 NOVEL PYRIDINE DERIVATIVES ORCHID RESEARCH LABORATORIES LIMITED (IN) 2007-03-15 WO claimed
WO-2007029062-A2 NOVEL PYRIDINE DERIVATIVES ORCHID RESEARCH LABORATORIES LIMITED (IN) 2007-03-15 WO disclosed