Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.42 |
| ▸ | DRD2 | P14416 | 10/20 | 0.42 |
| ▸ | HTR1A | P08908 | 8/20 | 0.42 |
| ▸ | HTR7 | P34969 | 6/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 6/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336644 | 0.88 | HTR7 (0.48) | HTR2AHTR7HTR6HTR2C | |
| SCHEMBL5462054 | 0.85 | DRD2 (0.51) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5474267 | 0.74 | HTR7 (0.57) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5461891 | 0.72 | HTR7 (0.39) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5473527 | 0.71 | HTR2A (0.44) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5481441 | 0.70 | DRD2 (0.46) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL5262985 | 0.66 | DRD3 (0.51) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL14339848 | 0.64 | DRD3 (0.76) | HTR2ADRD2HTR1AHTR2CDRD3 | |
| SCHEMBL5479077 | 0.59 | DRD2 (0.50) | HTR2ADRD2HTR1AHTR7HTR6 | |
| SCHEMBL14339849 | 0.58 | DRD3 (0.68) | HTR2ADRD2HTR1AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | claimed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |