Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335245 | 0.88 | HTR2A (0.42) | HTR7HTR6HTR2AHTR2C | |
| SCHEMBL5474267 | 0.87 | HTR7 (0.57) | HTR7HTR6HTR2AHTR2C | |
| SCHEMBL5462054 | 0.74 | DRD2 (0.51) | HTR7HTR6HTR2AHTR2C | |
| SCHEMBL5461891 | 0.71 | HTR7 (0.39) | HTR7HTR6HTR2AHTR2C | |
| SCHEMBL5468007 | 0.71 | HTR7 (0.51) | HTR7HTR6HTR2AHTR2CMEN1 | |
| SCHEMBL5473527 | 0.70 | HTR2A (0.44) | HTR7HTR6HTR2AHTR2C | |
| SCHEMBL5468109 | 0.70 | HTR2A (0.43) | HTR7HTR6HTR2AHTR2C | |
| SCHEMBL5336144 | 0.66 | HTR7 (0.55) | HTR7HTR6HTR2AHTR2CMEN1 | |
| SCHEMBL5481421 | 0.66 | HTR7 (0.47) | HTR7HTR6HTR2AHTR2CNAMPT | |
| SCHEMBL4824605 | 0.66 | HTR1A (0.61) | HTR7HTR6HTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | claimed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |