Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.51 |
| ▸ | DRD2 | P14416 | 13/20 | 0.51 |
| ▸ | HTR2A | P28223 | 11/20 | 0.50 |
| ▸ | HTR1A | P08908 | 9/20 | 0.50 |
| ▸ | HTR7 | P34969 | 5/20 | 0.50 |
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502557 | 0.86 | DRD3 (0.62) | DRD3DRD2HTR2AHTR1ADRD4 | |
| SCHEMBL5479077 | 0.85 | DRD2 (0.50) | DRD3DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL5336144 | 0.84 | HTR7 (0.55) | DRD3DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL5468095 | 0.84 | HTR1A (0.43) | DRD3DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL5470435 | 0.82 | HTR1A (0.48) | DRD3DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL5503596 | 0.82 | DRD2 (0.64) | DRD3DRD2HTR2AHTR1ADRD4 | |
| SCHEMBL5465737 | 0.82 | DRD2 (0.50) | DRD3DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL5471383 | 0.81 | DRD2 (0.48) | DRD2HTR2AHTR1AHTR7ADRA1A | |
| SCHEMBL5510364 | 0.80 | DRD2 (0.58) | DRD3DRD2HTR2AHTR1ADRD4 | |
| SCHEMBL5510402 | 0.80 | DRD2 (0.66) | DRD3DRD2HTR2AHTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | claimed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | claimed |
| US-20070299091-A1 | Azaindole Carboxamides | GMEINER PETER | 2007-12-27 | — | — | US | disclosed |
| EP-1771448-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006050976-A1 | AZAINDOLE CARBOXAMIDES | SCHWARZ PHARMA AG (DE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299091-A1 | Azaindole Carboxamides | TPH1, TPH2, HTR1A | DRD3 176/4885DRD2 64/4885HTR2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.