SCHEMBL533630

SCHEMBL533630

Fc1ccc(-c2ccccc2F)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.50
PTPRC P08575 1/20 0.50
PTPN1 P18031 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PTGS1 P23219 1/20 0.50
NPSR1 Q6W5P4 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
NR4A2 P43354 1/20 0.45
ACMSD Q8TDX5 1/20 0.44
HTR7 P34969 1/20 0.44
CSNK1D P48730 1/20 0.44
CSNK1E P49674 1/20 0.44
MAPK14 Q16539 1/20 0.44
DHODH Q02127 3/20 0.43
BACE1 P56817 1/20 0.43
TRPA1 O75762 1/20 0.43
HTR2C P28335 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL29088511 0.93 PTGS2 (0.50) PTGS2PTPRCPTPN1ALDH1A1MAPT
Methyl Alcohol SCHEMBL13725331 0.93 PTGS2 (0.50) PTGS2PTPRCPTPN1ALDH1A1MAPT
SCHEMBL12856701 0.92 PTPRC (0.56) PTPRCPTPN1ALDH1A1MAPTL3MBTL1
Sulfur Dioxide SCHEMBL28716860 0.91 ALDH1A1 (0.49) PTGS2PTPRCPTPN1ALDH1A1MAPT
Methylene Chloride SCHEMBL28982655 0.91 ALDH1A1 (0.49) PTGS2PTPRCPTPN1ALDH1A1MAPT
SCHEMBL18857290 0.89 PTPRC (0.56) PTGS2PTPRCPTPN1ALDH1A1MAPT
SCHEMBL30543293 0.84 ALDH1A1 (0.50) PTPRCPTPN1ALDH1A1MAPTL3MBTL1
SCHEMBL2140802 0.84 ALDH1A1 (0.50) PTPRCPTPN1ALDH1A1MAPTL3MBTL1
SCHEMBL201614 0.83 L3MBTL1 (0.50) PTPRCPTPN1ALDH1A1MAPTL3MBTL1
SCHEMBL19308529 0.83 PTPRC (0.46) PTGS2PTPRCPTPN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710919-A1 INJECTION PREPARATION AND PREPARATION METHOD THEREFOR, AND COMPATIBLE MEDICINAL LIQUID AND PREPARATION METHOD THEREFOR Ascentawits Pharmaceuticals, Ltd. (CN) 2026-03-18 EP disclosed
EP-4041732-B1 ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR ZHEJIANG METON PHARMACEUTICAL CO LTD (CN) 2026-03-18 EP disclosed
CN-112500811-B Polyimide adhesive, and preparation method and application thereof 南北兄弟药业投资有限公司 2025-04-18 CN disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-11760931-B2 Liquid-crystalline medium for use in a switching element MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-03-02 US disclosed
US-20230053362-A1 DICHROIC DYE COMPOSITION MERCK PATENT GMBH (DE) 2023-02-23 US disclosed
US-20230029961-A1 LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-02-02 US disclosed
US-20220220383-A1 METHOD FOR PREPARING A LIQUID CRYSTAL-BASED SWITCHING ELEMENT MERCK PATENT GMBH (DE) 2022-07-14 US disclosed
EP-4006012-A1 PROTEASOME INHIBITORS AND USES THEREOF Cornell University (US) 2022-06-01 EP disclosed
WO-2010009818-A1 BIS(PERFLUORALKYL)PHOSPHINOUS ACIDS AND DERIVATES AND USE THEREOF MERCK PATENT GMBH (DE) 2010-01-28 WO disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
CN-101432923-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP (JP) 2009-05-13 CN disclosed
US-20090041065-A1 Liquid Crystal Device CAMBRIDGE ENTERPRISE LIMITED (GB) 2009-02-12 US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
EP-1781758-A1 LIQUID CRYSTAL DEVICE Cambridge Enterprise Limited (GB) 2007-05-09 EP disclosed
WO-2006003435-A1 LIQUID CRYSTAL DEVICE CAMBRIDGE ENTERPRISE LIMITED (GB) 2006-01-12 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0629613-B1 Novel onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product NIPPON KAYAKU KK (JP) 1997-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY CXCR1, PYM1, F11 PTGS2 4239/4885PTPRC 1646/4885PTPN1 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.