Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335650 | 0.91 | EPAS1 (0.43) | CSNK2A1CSNK2A2CSNK2BSRCZAP70 | |
| SCHEMBL5340653 | 0.85 | EPAS1 (0.39) | CSNK2A1CSNK2A2CSNK2BSRCZAP70 | |
| SCHEMBL5330964 | 0.83 | CSNK2A1 (0.35) | CSNK2A1CSNK2A2CSNK2BSRCZAP70 | |
| Hydrochloric Acid SCHEMBL5334356 | 0.82 | CSNK2A1 (0.35) | CSNK2A1CSNK2A2CSNK2BSRCZAP70 | |
| SCHEMBL5312247 | 0.81 | MAPT (0.42) | CSNK2A1CSNK2A2CSNK2BNPC1RAB9A | |
| SCHEMBL5376227 | 0.78 | KMT2A (0.45) | SYKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5329633 | 0.76 | KMT2A (0.52) | SRCRAB9AMEN1KMT2A | |
| SCHEMBL5333560 | 0.75 | MEN1 (0.55) | CSNK2A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5332098 | 0.75 | MEN1 (0.49) | CSNK2A1NPC1MEN1KMT2ATP53 | |
| SCHEMBL5313426 | 0.73 | PTGS1 (0.46) | CSNK2A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |