Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335650 | 0.91 | EPAS1 (0.43) | EPAS1CSNK2A1CSNK2A2CSNK2BNPC1 | |
| SCHEMBL5336441 | 0.85 | CSNK2A1 (0.39) | EPAS1CSNK2A1CSNK2A2CSNK2BNPC1 | |
| SCHEMBL5330964 | 0.83 | CSNK2A1 (0.35) | EPAS1CSNK2A1CSNK2A2CSNK2BNPC1 | |
| Hydrochloric Acid SCHEMBL5334356 | 0.82 | CSNK2A1 (0.35) | EPAS1CSNK2A1CSNK2A2CSNK2BNPC1 | |
| SCHEMBL5312247 | 0.81 | MAPT (0.42) | CSNK2A1CSNK2A2CSNK2BNPC1RAB9A | |
| SCHEMBL5376227 | 0.78 | KMT2A (0.45) | NPC1RAB9AMEN1KMT2ASYK | |
| SCHEMBL5335403 | 0.77 | NPC1 (0.46) | EPAS1CSNK2A1CSNK2A2CSNK2BNPC1 | |
| SCHEMBL5329633 | 0.76 | KMT2A (0.52) | RAB9AMEN1KMT2ASRCCLK1 | |
| SCHEMBL5333560 | 0.75 | MEN1 (0.55) | CSNK2A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5332098 | 0.75 | MEN1 (0.49) | CSNK2A1NPC1MEN1KMT2ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |