Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315946 | 1.00 | KCNH2 (0.51) | KCNH2KCNA5HTR1ADRD2HTR7 | |
| SCHEMBL5315724 | 0.95 | KCNH2 (0.56) | KCNH2HTR1ADRD2HTR7HTR6 | |
| SCHEMBL5315943 | 0.91 | KCNH2 (0.51) | KCNH2KCNA5HTR1ADRD2HTR7 | |
| SCHEMBL5314900 | 0.91 | KCNA5 (0.55) | KCNH2KCNA5HTR1ADRD2HTR7 | |
| SCHEMBL5315933 | 0.90 | HTR1A (0.47) | KCNH2HTR1ADRD2HTR7HTR6 | |
| SCHEMBL5317453 | 0.89 | KMT2A (0.48) | KCNH2HTR1ADRD2HTR7HTR6 | |
| SCHEMBL5319012 | 0.88 | KCNH2 (0.43) | KCNH2KCNA5HTR1ADRD2HTR7 | |
| SCHEMBL5314736 | 0.86 | KMT2A (0.50) | HTR1ADRD2HTR7HTR6KMT2A | |
| SCHEMBL5314598 | 0.86 | KCNH2 (0.53) | KCNH2KCNA5HTR1ADRD2HTR7 | |
| SCHEMBL5316933 | 0.86 | KCNH2 (0.47) | KCNH2KCNA5HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |