Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331543 | 0.91 | PCSK9 (0.46) | HTR6ALDH3A1NOD1HDAC1HDAC2 | |
| SCHEMBL5327664 | 0.90 | HTR6 (0.47) | HTR6HDAC1HDAC2HDAC6PCSK9 | |
| SCHEMBL5326308 | 0.89 | NOD1 (0.45) | HTR6NOD1HDAC1HDAC2HDAC6 | |
| SCHEMBL5407866 | 0.89 | PTGDR2 (0.52) | HTR6ALDH3A1PTGDR2PTGDRLMNA | |
| SCHEMBL5329965 | 0.87 | PTGDR2 (0.54) | HTR6PTGDR2PTGDRLMNA | |
| SCHEMBL5328971 | 0.87 | HTR6 (0.48) | HTR6PTGDR2PTGDRNOD1LMNA | |
| SCHEMBL5420513 | 0.86 | PTGDR2 (0.44) | HTR6PTGDR2PTGDRLMNA | |
| SCHEMBL5327663 | 0.84 | HTR6 (0.49) | HTR6PCSK9LMNAMAPTTSHR | |
| SCHEMBL5328962 | 0.84 | PTGDR2 (0.53) | HTR6PTGDR2PTGDRLMNAMAPT | |
| SCHEMBL5330909 | 0.84 | HTR6 (0.52) | HTR6PTGDR2PTGDRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |