Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509860 | 1.00 | NPC1 (0.41) | NPC1MAPTNFKB1MAPK1RAB9A | |
| SCHEMBL5335130 | 0.92 | GABRP (0.42) | NPC1MAPTNFKB1MAPK1RAB9A | |
| SCHEMBL4526112 | 0.92 | GABRP (0.42) | NPC1MAPTNFKB1MAPK1RAB9A | |
| SCHEMBL13854951 | 0.91 | GABRP (0.38) | NPC1MAPTNFKB1MAPK1RAB9A | |
| SCHEMBL4514929 | 0.90 | NPC1 (0.48) | NPC1MAPTNFKB1MAPK1RAB9A | |
| SCHEMBL4505793 | 0.87 | HPGD (0.42) | NPC1RAB9AL3MBTL1METKDR | |
| SCHEMBL4509997 | 0.84 | MET (0.39) | METKDR | |
| SCHEMBL5331086 | 0.84 | MET (0.39) | METKDR | |
| SCHEMBL4238865 | 0.84 | GABRP (0.41) | NPC1MAPTNFKB1MAPK1RAB9A | |
| SCHEMBL5332762 | 0.83 | ALDH1A1 (0.32) | NPC1MAPTMAPK1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |