SCHEMBL5331086

SCHEMBL5331086

CCN1C(=O)OCC1Cc1ccc(Oc2ccc(Nc3ccccn3)cc2F)cc1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MET P08581 3/20 0.39
AXL P30530 2/20 0.39
KDR P35968 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4509997 1.00 MET (0.39) METAXLKDR
SCHEMBL4516481 0.90 MET (0.39) METKDR
SCHEMBL5339765 0.90 MET (0.39) METKDR
SCHEMBL4518401 0.89 PDE10A (0.41)
SCHEMBL5333541 0.89 PDE10A (0.41)
SCHEMBL4239377 0.89 MET (0.38) METAXLKDR
SCHEMBL4508563 0.86 SCN9A (0.36) METKDR
SCHEMBL4503291 0.85 KMT2A (0.45) MET
SCHEMBL5338964 0.85 KMT2A (0.45) MET
SCHEMBL5337291 0.84 NPC1 (0.41) METKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007029062-A2 NOVEL PYRIDINE DERIVATIVES ORCHID RESEARCH LABORATORIES LIMITED (IN) 2007-03-15 WO disclosed