SCHEMBL5337592

SCHEMBL5337592

CCCCCNC(=O)c1cc(Cl)c2nc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)n2c1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.52
TSPO P30536 1/20 0.44
CNR2 P34972 2/20 0.43
TP53 P04637 1/20 0.43
AKT1 P31749 1/20 0.42
AKT2 P31751 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337517 0.93 CNR1 (0.50) CNR1TSPOCNR2TP53
SCHEMBL5342400 0.81 AKT1 (0.50) TSPOAKT1AKT2
SCHEMBL5342248 0.78 TSPO (0.47) CNR1TSPOTP53AKT1AKT2
SCHEMBL5341492 0.77 CNR1 (0.43) CNR1TSPOTP53
SCHEMBL5341020 0.73 AKT1 (0.50) CNR1AKT1AKT2
SCHEMBL5343352 0.73 AKT1 (0.49) TSPOTP53AKT1AKT2
SCHEMBL5342475 0.73 AKT1 (0.59) AKT1AKT2
SCHEMBL5338301 0.72 AKT1 (0.48) AKT1AKT2
SCHEMBL4075789 0.71 CNR1 (0.79) CNR1CNR2
SCHEMBL4075955 0.70 CNR1 (0.66) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007086080-A2 NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LIMITED (IN) 2007-08-02 WO claimed
WO-2007086080-A2 NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLENMARK PHARMACEUTICALS LIMITED (IN) 2007-08-02 WO disclosed