Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337592 | 0.93 | CNR1 (0.52) | CNR1CNR2TP53TSPO | |
| SCHEMBL5343352 | 0.81 | AKT1 (0.49) | TP53TSPO | |
| SCHEMBL5342248 | 0.78 | TSPO (0.47) | CNR1TP53TSPO | |
| SCHEMBL5341492 | 0.75 | CNR1 (0.43) | CNR1TP53TSPO | |
| SCHEMBL5340948 | 0.73 | EPAS1 (0.46) | CNR1TP53 | |
| SCHEMBL5341020 | 0.73 | AKT1 (0.50) | CNR1 | |
| SCHEMBL5340780 | 0.73 | AKT1 (0.59) | TP53 | |
| SCHEMBL5342400 | 0.72 | AKT1 (0.50) | TSPO | |
| SCHEMBL5317129 | 0.72 | AKT1 (0.48) | CNR1 | |
| SCHEMBL4089756 | 0.72 | CNR1 (0.77) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |