Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341492 | 0.84 | CNR1 (0.43) | TSPOCNR1NAMPTNPC1RAB9A | |
| SCHEMBL5337517 | 0.78 | CNR1 (0.50) | TSPOCNR1TP53 | |
| SCHEMBL5337592 | 0.78 | CNR1 (0.52) | TSPOCNR1AKT1AKT2TP53 | |
| SCHEMBL5338039 | 0.72 | AKT1 (0.45) | TSPOAKT1AKT2SMN1; SMN2 | |
| SCHEMBL20808133 | 0.70 | TP53 (0.45) | CNR1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL20808078 | 0.70 | TP53 (0.45) | CNR1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL20808102 | 0.70 | TP53 (0.45) | CNR1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL20808136 | 0.70 | TP53 (0.45) | CNR1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL13356507 | 0.69 | NPC1 (0.77) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL5341752 | 0.68 | AKT1 (0.53) | TSPOAKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |