Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351259 | 0.82 | MEN1 (0.46) | P2RX7KMT2AMEN1TSHRHTT | |
| SCHEMBL5335055 | 0.81 | NAMPT (0.46) | KMT2AMEN1TSHRHTTNPC1 | |
| SCHEMBL5344217 | 0.76 | LMNA (0.51) | KMT2AMEN1HTTNPC1RAB9A | |
| SCHEMBL5318651 | 0.76 | HDAC1 (0.50) | CNR1CNR2RAB9AHDAC6 | |
| SCHEMBL5339245 | 0.75 | CNR1 (0.43) | KMT2ACNR1CNR2NPC1RAB9A | |
| SCHEMBL5338077 | 0.69 | HTR4 (0.52) | KMT2AMEN1TSHRHTTCNR1 | |
| SCHEMBL3709355 | 0.67 | KCNQ3 (0.62) | KMT2AMEN1TSHRHTTCNR1 | |
| SCHEMBL5351251 | 0.67 | NPC1 (0.52) | KMT2AMEN1TSHRHTTPDE4A | |
| SCHEMBL6026093 | 0.66 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL10283546 | 0.66 | MAPK14 (0.50) | KMT2AMEN1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |