Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335055 | 0.84 | NAMPT (0.46) | LMNAALDH1A1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL5318651 | 0.79 | HDAC1 (0.50) | RAB9AMAPTTP53POLBRXFP1 | |
| SCHEMBL5333974 | 0.78 | NPC1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5338080 | 0.76 | P2RX7 (0.46) | KMT2ARAB9ANPC1MEN1HTT | |
| SCHEMBL5339245 | 0.76 | CNR1 (0.43) | KMT2ARAB9ANPC1MAPTTP53 | |
| SCHEMBL5344215 | 0.69 | DHODH (0.56) | LMNAALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL28551980 | 0.69 | RAB9A (0.74) | LMNAKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15529130 | 0.68 | KDM4E (0.48) | LMNAALDH1A1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL28601911 | 0.67 | HIF1A (0.85) | LMNAKMT2ARAB9ANPC1MAPT | |
| SCHEMBL8163393 | 0.67 | MCHR1 (0.77) | LMNAALDH1A1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |