Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333974 | 0.81 | NPC1 (0.47) | SLC22A12NTRK1PIM1ACVR1ANO1 | |
| SCHEMBL5335055 | 0.80 | NAMPT (0.46) | NAMPTNPC1RAB9AKMT2A | |
| SCHEMBL5335422 | 0.79 | SPTLC1 (0.45) | CNR1TP53MDM2SLC22A12HSD11B1 | |
| SCHEMBL5344217 | 0.76 | LMNA (0.51) | TP53NPC1MAPTRAB9AKMT2A | |
| SCHEMBL5318651 | 0.76 | HDAC1 (0.50) | CNR1TP53MDM2CNR2NAMPT | |
| SCHEMBL5338080 | 0.75 | P2RX7 (0.46) | CNR1CNR2NPC1RAB9AKMT2A | |
| SCHEMBL20312855 | 0.69 | SMN1; SMN2 (0.46) | TP53MAPTRAB9AKMT2A | |
| SCHEMBL5341359 | 0.69 | NPC1 (0.51) | SLC22A12NTRK1PIM1ACVR1ANO1 | |
| SCHEMBL7317792 | 0.66 | ALDH1A3 (0.54) | TDP1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL5339242 | 0.66 | ALDH1A1 (0.56) | CNR1TP53TDP1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |