Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619718 | 0.82 | NR3C2 (0.44) | NR3C2MGLLGAANR3C1MMP12 | |
| SCHEMBL21972598 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL21972597 | 0.75 | MGLL (0.46) | NR3C2MGLLSYK | |
| SCHEMBL19250511 | 0.75 | NR3C2 (0.44) | NR3C2NR3C1SYKMMP12 | |
| SCHEMBL2489889 | 0.74 | NR3C2 (0.50) | NR3C2NR3C1MMP12 | |
| SCHEMBL21400918 | 0.73 | NR3C2 (0.42) | NR3C2GAANR3C1SYKMMP12 | |
| SCHEMBL21972595 | 0.73 | ALDH1A1 (0.46) | MGLL | |
| SCHEMBL7980639 | 0.73 | SYK (0.44) | NR3C2NR3C1SYKMMP12 | |
| SCHEMBL19629922 | 0.72 | NR3C2 (0.41) | NR3C2MGLLGAANR3C1MMP12 | |
| SCHEMBL14611166 | 0.72 | PDE3B (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |