Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4503291 | 1.00 | KMT2A (0.45) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4510231 | 0.92 | KMT2A (0.43) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4238022 | 0.90 | KMT2A (0.41) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4506024 | 0.90 | RAB9A (0.51) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL5336561 | 0.90 | RAB9A (0.51) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4508563 | 0.87 | SCN9A (0.36) | HRH3MET | |
| SCHEMBL4509997 | 0.85 | MET (0.39) | MET | |
| SCHEMBL5331086 | 0.85 | MET (0.39) | MET | |
| SCHEMBL4238041 | 0.84 | RAB9A (0.42) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL5333522 | 0.83 | HSPB1 (0.36) | MAPTALDH1A1SMN1; SMN2PKMHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |