Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.63 |
| ▸ | FLT1 | P17948 | 5/20 | 0.43 |
| ▸ | FLT4 | P35916 | 5/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SIRT7 | Q9NRC8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14466984 | 0.92 | VCP (0.63) | VCPFLT1FLT4KDRCFTR | |
| SCHEMBL5333251 | 0.85 | IMPDH2 (0.55) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL5339016 | 0.82 | VCP (0.58) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL14465936 | 0.82 | IMPDH2 (0.61) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL5316737 | 0.82 | IMPDH2 (0.55) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL5342641 | 0.80 | TRPV1 (0.61) | FLT1FLT4KDRIMPDH2EIF2AK2 | |
| SCHEMBL5334372 | 0.78 | KDR (0.59) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL5469678 | 0.78 | FLT1 (0.68) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL5336169 | 0.78 | MEN1 (0.51) | VCPFLT1FLT4KDRIMPDH2 | |
| SCHEMBL5334965 | 0.77 | VCP (0.57) | VCPFLT1FLT4KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | claimed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076161-A2 | COMPOUNDS WITH THERAPEUTIC ACTIVITY | MYRIAD GENETICS, INC (US) | 2007-07-05 | — | — | WO | disclosed |