Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484195 | 1.00 | GPR84 (0.35) | GPR84FDPSSPHK1FFAR1LMNA | |
| SCHEMBL4247123 | 0.83 | GPR84 (0.43) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL6737764 | 0.83 | GPR84 (0.43) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL29199615 | 0.79 | GPR84 (0.40) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL31135148 | 0.79 | GPR84 (0.40) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL28015957 | 0.79 | GPR84 (0.40) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL31135122 | 0.78 | DNM1 (0.42) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL27812177 | 0.76 | OPRM1 (0.39) | GPR84SPHK1FFAR1LMNACYP2D6 | |
| SCHEMBL14995732 | 0.75 | FDPS (0.44) | GPR84FDPSSPHK1FFAR1LMNA | |
| SCHEMBL337206 | 0.75 | FDPS (0.44) | GPR84FDPSSPHK1FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235683-B2 | Organochlorosilane and dipodal silane compounds | GELEST INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235682-B2 | Process for manufacturing organochlorosilanes and dipodal silanes | GELEST INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-20070060765-A1 | ORGANOCHLOROSILANE AND DIPODAL SILANE COMPOUNDS | GELEST, INC. (US) | 2007-03-15 | — | — | US | disclosed |
| US-20050027138-A1 | Processes for manufacturing organochlorosilanes and dipodal silanes and silanes made thereby | GELEST INC. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060765-A1 | ORGANOCHLOROSILANE AND DIPODAL SILANE COMPOUNDS | DDT, PIK3C3, PKD1 | GPR84 3393/4885FDPS 1369/4885SPHK1 366/4885 |
| US-20050027138-A1 | Processes for manufacturing organochlorosilanes and dipodal silanes and silanes made thereby | DDT, PIK3C3, PIK3CD | GPR84 3426/4885FDPS 852/4885SPHK1 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.