Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321208 | 0.80 | MAPT (0.42) | KMT2AGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL19707851 | 0.79 | KMT2A (0.45) | KMT2AGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL22769142 | 0.75 | SAE1 (0.44) | KMT2AGAASMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL27469291 | 0.74 | HPGD (0.47) | KMT2AGAARAB9ANPC1L3MBTL1 | |
| SCHEMBL7960771 | 0.74 | GPR88 (0.53) | KMT2AGAARAB9AMEN1MAPT | |
| SCHEMBL4332921 | 0.73 | KMT2A (0.41) | KMT2AGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6475227 | 0.73 | LMNA (0.42) | KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL19324983 | 0.73 | GAA (0.55) | KMT2AGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28355844 | 0.72 | PTGS2 (0.46) | KMT2AGAASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5510420 | 0.72 | GAA (0.58) | KMT2AGAASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062316-A2 | TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR ANTI-MANNICH REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-05-31 | — | — | WO | disclosed |