Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321208 | 0.79 | MAPT (0.42) | MAPTTSHRMEN1KMT2AKDM4E | |
| SCHEMBL19707399 | 0.78 | MAPT (0.45) | SAE1UBA2ABCC9KCNJ11MAPT | |
| SCHEMBL5339625 | 0.75 | KMT2A (0.49) | SAE1UBA2MAPTLMNAHTT | |
| SCHEMBL19966755 | 0.74 | ABCC9 (0.51) | SAE1UBA2ABCC9KCNJ11HTT | |
| SCHEMBL11957638 | 0.73 | KIF11 (0.47) | SAE1UBA2ABCC9KCNJ11MAPT | |
| SCHEMBL9259276 | 0.71 | GSK3B (0.44) | MAPTHTTMEN1KMT2AKDM4E | |
| SCHEMBL7868519 | 0.71 | EPHX2 (0.43) | MAPTHTTMEN1KMT2ACTBP2 | |
| SCHEMBL13656123 | 0.71 | ABCC9 (0.52) | SAE1UBA2ABCC9KCNJ11MAPT | |
| SCHEMBL27491369 | 0.71 | CNR2 (0.43) | SAE1UBA2ABCC9KCNJ11MAPT | |
| Acetoacetic Acid SCHEMBL27717062 | 0.70 | SAE1 (0.43) | SAE1UBA2MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244460-A1 | HETEROAROMATIC ACETAMIDE DERIVATIVE, AND PREPARATION AND USE THEREOF | 杭州维坦医药科技有限公司 | 2020-12-10 | — | — | WO | disclosed |