Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516481 | 1.00 | MET (0.39) | METKDRP2RX3 | |
| SCHEMBL5331086 | 0.90 | MET (0.39) | METKDR | |
| SCHEMBL4509997 | 0.90 | MET (0.39) | METKDR | |
| SCHEMBL4238872 | 0.89 | P2RX3 (0.39) | METKDRP2RX3 | |
| SCHEMBL4506585 | 0.88 | PDE10A (0.42) | — | |
| SCHEMBL4511519 | 0.88 | PDE10A (0.42) | — | |
| SCHEMBL4499595 | 0.85 | KDR (0.38) | METKDR | |
| SCHEMBL4510231 | 0.84 | KMT2A (0.43) | P2RX3 | |
| SCHEMBL4511394 | 0.84 | BCL6 (0.43) | METKDRP2RX3 | |
| SCHEMBL5335130 | 0.83 | GABRP (0.42) | METKDRP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |