Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
| ▸ | POLR1A | O95602 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340752 | 0.82 | CNR1 (0.53) | CNR1AKT1AKT2 | |
| SCHEMBL5341869 | 0.80 | AKT2 (0.47) | AKT1AKT2KDM4EHSD17B10 | |
| SCHEMBL5318509 | 0.79 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL5355542 | 0.75 | CNR1 (0.59) | CNR1CNR2HPGDKDM4EALDH1A1 | |
| SCHEMBL5337928 | 0.74 | AKT1 (0.52) | AKT1AKT2KDM4EHSD17B10 | |
| SCHEMBL5478849 | 0.72 | AKT1 (0.55) | AKT1AKT2KDM4EHSD17B10 | |
| SCHEMBL4080428 | 0.72 | CNR1 (1.00) | CNR1CNR2HPGDKDM4EALDH1A1 | |
| SCHEMBL5340645 | 0.71 | AKT1 (0.54) | AKT1AKT2KDM4EHSD17B10 | |
| SCHEMBL5337592 | 0.69 | CNR1 (0.52) | CNR1CNR2AKT1AKT2 | |
| SCHEMBL5337517 | 0.69 | CNR1 (0.50) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |