Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 5/20 | 0.48 |
| ▸ | CES1 | P23141 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313862 | 0.81 | GAA (0.52) | ALDH1A1RAB9AKMT2ANPC1TSHR | |
| SCHEMBL4877612 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTRAB9AHSP90AA1CES2 | |
| SCHEMBL816507 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AHSP90AA1CES2 | |
| SCHEMBL3281298 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTRAB9AHSP90AA1CES2 | |
| Benzil SCHEMBL1422480 | 0.74 | CES2 (0.78) | ALDH1A1RAB9ACES2CES1NPC1 | |
| SCHEMBL815706 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTRAB9AHSP90AA1CES2 | |
| Trimethylammonium SCHEMBL27814543 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTRAB9AHSP90AA1CES2 | |
| SCHEMBL2973819 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9AHSP90AA1KMT2A | |
| SCHEMBL30062 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9ACES2CES1 | |
| SCHEMBL4039494 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110025823-A | A kind of bone cement material and preparation method thereof | 太原理工大学 | 2019-07-19 | — | — | CN | claimed |
| CN-110025823-A | A kind of bone cement material and preparation method thereof | 太原理工大学 | 2019-07-19 | — | — | CN | disclosed |
| US-7276511-B2 | Benzylamine derivative | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-7229751-B2 | Silver salt photothermographic dry imaging material and image forming method using the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7211373-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| US-20060194841-A1 | E.g., N-{2-(3,4-dichlorophenyl)-2-[(3,3-diphenylpropionyl)-methylamino]-4-{spiro[benzo(c)thiophene-1(3H),4'-piperidine]-(2S)-oxide}-1'-yl-butyl}-3,3,3-trifluoro-N-methyl-propionamide hydrochloride, NK-1 or NK-2 receptor antagonists; irritable bowel syndrome, pain, anxiety, COPD, headaches and vomiting | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| US-7083908-B2 | Photothermographic material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| EP-1650189-A1 | BENZYLAMINE DERIVATIVE | Zeria Pharmaceutical Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-6949332-B2 | Silver halide emulsion and method of preparing the same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20050158675-A9 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2005-07-21 | — | — | US | disclosed |
| US-6689554-B2 | ENHANCED SPEED; SUPPRESSED FOG | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20040023174-A1 | Photothermographic material | OHZEKI TOMOYUKI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6686140-B2 | Silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20040018454-A1 | Silver halide color photosensitive material and photographic product | FUJIFILM CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20030224307-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2003-12-04 | — | — | US | disclosed |
| US-20030224309-A1 | Silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. | 2003-12-04 | — | — | US | disclosed |
| US-20030207221-A1 | Silver halide emulsion and silver halide photographic lightsensitive material | FUJI PHOTO FILM CO., LTD. | 2003-11-06 | — | — | US | disclosed |
| US-20030203329-A1 | Silver halide photosensitive material | FUJI PHOTO FILM CO., LTD. | 2003-10-30 | — | — | US | disclosed |
| US-20030194638-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2003-10-16 | — | — | US | disclosed |
| EP-1300726-A1 | Photothermographic material comprising fragmentable electron donor | FUJI PHOTO FILM CO., LTD. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194841-A1 | E.g., N-{2-(3,4-dichlorophenyl)-2-[(3,3-diphenylpropionyl)-methylamino]-4-{spiro[benzo(c)thiophene-1(3H),4'-piperidine]-(2S)-oxide}-1'-yl-butyl}-3,3,3-trifluoro-N-methyl-propionamide hydrochloride, NK-1 or NK-2 receptor antagonists; irritable bowel syndrome, pain, anxiety, COPD, headaches and vomiting | KCNAB1, BDKRB2, ARRB1 | ALDH1A1 1065/4885MAPT 4040/4885RAB9A 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.