Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066451 | 0.83 | NOS3 (0.55) | NOS3NOS1NOS2TSHRKDM4E | |
| SCHEMBL15200880 | 0.83 | NOS3 (0.61) | NOS3NOS1NOS2TAAR1LOXL2 | |
| SCHEMBL13337725 | 0.83 | NOS3 (0.55) | NOS3NOS1NOS2HRH1LOXL2 | |
| Hydrochloric Acid SCHEMBL11420925 | 0.82 | NOS3 (0.53) | NOS3NOS1NOS2HRH1LOXL2 | |
| SCHEMBL218290 | 0.81 | NOS3 (0.61) | NOS3NOS1NOS2LOXL2TSHR | |
| SCHEMBL2552826 | 0.80 | NOS2 (0.52) | NOS3NOS1NOS2TSHRKDM4E | |
| SCHEMBL6637337 | 0.80 | NOS3 (0.52) | NOS3NOS1NOS2TSHRKDM4E | |
| SCHEMBL11563922 | 0.79 | NOS3 (0.59) | NOS3NOS1NOS2LOXL2TSHR | |
| SCHEMBL2550616 | 0.78 | NOS3 (0.50) | NOS3NOS1NOS2TSHRKDM4E | |
| SCHEMBL31280277 | 0.78 | NOS3 (0.50) | NOS3NOS1NOS2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |