Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40418 | 0.89 | AKR1B1 (0.58) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| Ethylene Glycol SCHEMBL6232155 | 0.88 | AKR1B1 (0.52) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| Ethylene Glycol SCHEMBL6229361 | 0.88 | AKR1B1 (0.52) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| 1,3-Propanediol SCHEMBL6335045 | 0.85 | AKR1B1 (0.48) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| Phenylacetic Acid SCHEMBL18139273 | 0.80 | AKR1B1 (0.74) | AKR1B1LMNAGAATSHRPOLB | |
| SCHEMBL6235820 | 0.79 | CA2 (0.50) | AKR1B1LMNAGAATSHRKDM4E | |
| SCHEMBL70565 | 0.75 | AKR1B1 (0.71) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| Hydrochloric Acid SCHEMBL8922940 | 0.73 | AKR1B1 (0.68) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL14704483 | 0.73 | AKR1B1 (0.56) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL8986802 | 0.73 | ALDH1A1 (0.39) | AKR1B1CYP1A2CYP2C19POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927247-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2005-08-09 | — | — | US | claimed |
| EP-1521803-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | The College of William and Mary (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2003106550-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2003-12-24 | — | — | WO | claimed |
| US-20030220429-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-11-27 | — | — | US | claimed |
| US-7312266-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-12-25 | — | — | US | disclosed |
| US-6927247-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1521803-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | The College of William and Mary (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2005-03-03 | — | — | US | disclosed |
| WO-2003106550-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2003-12-24 | — | — | WO | disclosed |
| US-20030220429-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | TST, LANCL1, TTPA | AKR1B1 2084/4885CYP1A2 3114/4885CYP2C19 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.