Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30161536 | 1.00 | TRPV4 (0.47) | TRPV4L3MBTL1GUSBCA12CA1 | |
| SCHEMBL1991714 | 0.94 | TRPV4 (0.50) | TRPV4L3MBTL1GUSBCA12CA1 | |
| SCHEMBL4426923 | 0.92 | TRPV4 (0.48) | TRPV4L3MBTL1GUSBCA12CA1 | |
| SCHEMBL3912870 | 0.80 | TRPV4 (0.46) | TRPV4L3MBTL1CA12CA1CA2 | |
| SCHEMBL31556482 | 0.80 | HTT (0.49) | TRPV4L3MBTL1CA12CA1CA2 | |
| SCHEMBL788091 | 0.80 | HTT (0.49) | TRPV4L3MBTL1CA12CA1CA2 | |
| SCHEMBL3948181 | 0.80 | TRPV4 (0.46) | TRPV4L3MBTL1CA12CA1CA2 | |
| SCHEMBL1035731 | 0.80 | GAA (0.55) | TRPV4L3MBTL1CA12CA1CA2 | |
| SCHEMBL3483762 | 0.80 | TSHR (0.44) | TRPV4L3MBTL1CA12CA1CA2 | |
| SCHEMBL5635695 | 0.80 | TSHR (0.50) | TRPV4L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-4020249-A | Photodegradable polyolefins containing haloalkyl- or halobenzene-sulfonyl halides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-26 | — | — | US | claimed |
| US-12630529-B2 | GCN2 modulator compounds | Alesta Therapeutics BV (NL) | 2026-05-19 | — | — | US | disclosed |
| US-20250115687-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORP USA (US) | 2025-04-10 | — | — | US | disclosed |
| CN-117402124-A | Aryl sulfonamide compound and anti-influenza application thereof | 中国医学科学院医药生物技术研究所 | 2024-01-16 | — | — | CN | disclosed |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2023-05-11 | — | — | US | disclosed |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2023-05-11 | — | — | US | disclosed |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2023-05-11 | — | — | US | disclosed |
| CN-115768750-A | GCN2 modulator compounds | 阿莱斯塔治疗公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-4107146-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2022-12-28 | — | — | EP | disclosed |
| US-4071351-A | Sulfonamide herbicide antidote compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071350-A | THIOCARBAMATES | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071349-A | Sulfonamide herbicide antidote compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4039731-A | PHOTODEGRADABLE POLYOLEFINS CONTAINING NITROHALOALKANES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-08-02 | — | — | US | disclosed |
| US-4029809-A | Method of protecting plants from pathogens with cyanomethyl aryl sulfonates | PENNWALT CORPORATION (US) | 1977-06-14 | — | — | US | disclosed |
| US-4021229-A | THIOCARBAMATE | STAUFFER CHEMICAL COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
| US-4020249-A | Photodegradable polyolefins containing haloalkyl- or halobenzene-sulfonyl halides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-26 | — | — | US | disclosed |
| US-4017666-A | POLLUTION CONTROL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | disclosed |
| US-3968096-A | Photodegradable polyolefins containing an halogenated nitrile | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630529-B2 | GCN2 modulator compounds | NR3C1, GCN1, EIF2AK4 | TRPV4 2630/4885L3MBTL1 1704/4885GUSB 3646/4885 |
| US-20230143059-A1 | GCN2 MODULATOR COMPOUNDS | EIF2AK4, GPR119, GCN1 | TRPV4 2116/4885L3MBTL1 2173/4885GUSB 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.