SCHEMBL534216

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL533699	0.78	RAB9A (0.44)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL1029102	0.78	ALDH1A1 (0.66)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL534232	0.76	CYP19A1 (0.41)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL533381	0.76	GAA (0.61)	ALDH1A1RAB9AKDM4EMAPTHTT
	SCHEMBL533498	0.76	IDH1 (0.41)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL533522	0.76	ALDH1A1 (0.37)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL533127	0.72	ALOX5 (0.39)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL533594	0.72	LOXL2 (0.41)	ALDH1A1RAB9AKDM4EMAPTLMNA
	SCHEMBL533303	0.72	ALDH1A1 (0.34)	ALDH1A1RAB9AALOX5CYP3A4KDM4E
	SCHEMBL714474	0.72	KDM4E (0.69)	ALDH1A1RAB9ACYP3A4KDM4EAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.