SCHEMBL5342293

SCHEMBL5342293

c1ccc([C](c2ccccc2)N2CCOCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.58
HPGD P15428 1/20 0.58
TSHR P16473 1/20 0.58
FAAH O00519 1/20 0.55
MGLL Q99685 1/20 0.55
NCOA3 Q9Y6Q9 1/20 0.55
SMN1; SMN2 Q16637 4/20 0.54
GAA P10253 2/20 0.54
KMT2A Q03164 4/20 0.50
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
LMNA P02545 2/20 0.50
MEN1 O00255 1/20 0.50
AKR1C3 P42330 1/20 0.50
HTT P42858 1/20 0.50
CASP3 P42574 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8727982 0.83 MGLL (0.59) PHGDHHPGDTSHRFAAHMGLL
Morpholino(Phenyl)Methanethione SCHEMBL9180076 0.81 MGLL (0.79) PHGDHHPGDTSHRFAAHMGLL
SCHEMBL27890355 0.79 HPGD (0.54) HPGDGAAKMT2ACYP2C9MEN1
SCHEMBL946143 0.79 HPGD (0.86) PHGDHHPGDTSHRSMN1; SMN2GAA
SCHEMBL5949372 0.79 PHGDH (0.54) PHGDHHPGDTSHRFAAHMGLL
SCHEMBL10419001 0.79 RAB9A (0.53) PHGDHHPGDTSHRFAAHMGLL
SCHEMBL8884084 0.79 RAB9A (0.53) PHGDHHPGDTSHRFAAHMGLL
SCHEMBL30449295 0.78 HPGD (0.83) PHGDHHPGDTSHRSMN1; SMN2GAA
Ammonia Solution, Strong SCHEMBL6028542 0.78 HPGD (0.83) PHGDHHPGDTSHRSMN1; SMN2GAA
SCHEMBL27798296 0.77 HPGD (0.63) HPGDGAAKMT2ACYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7229751-B2 Silver salt photothermographic dry imaging material and image forming method using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-06-12 US disclosed
US-7211373-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2007-05-01 US disclosed
US-7083908-B2 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2006-08-01 US disclosed
EP-1300726-B1 Photothermographic material comprising fragmentable electron donor FUJI PHOTO FILM CO LTD (JP) 2005-12-21 EP disclosed
US-6949332-B2 Silver halide emulsion and method of preparing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-09-27 US disclosed
US-20050158675-A9 Photothermographic material FUJIFILM CORPORATION (JP) 2005-07-21 US disclosed
US-20050147931-A1 Process for manufacturing a photothermographic material FUJI PHOTO FILM CO., LTD. 2005-07-07 US disclosed
US-20050136366-A1 Silver salt photothermographic dry imaging material and image forming method using the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2005-06-23 US disclosed
US-6855488-B2 Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-02-15 US disclosed
US-20050032007-A1 Silver halide emulsion and method of preparing the same FUJI PHOTO FILM CO., LTD. 2005-02-10 US disclosed
US-6689554-B2 ENHANCED SPEED; SUPPRESSED FOG FUJI PHOTO FILM CO., LTD. (JP) 2004-02-10 US disclosed
US-20040023174-A1 Photothermographic material OHZEKI TOMOYUKI (JP) 2004-02-05 US disclosed
US-6686140-B2 Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2004-02-03 US disclosed
US-20040018454-A1 Silver halide color photosensitive material and photographic product FUJIFILM CORPORATION (JP) 2004-01-29 US disclosed
US-20030224307-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2003-12-04 US disclosed
US-20030224309-A1 Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. 2003-12-04 US disclosed
US-20030207221-A1 Silver halide emulsion and silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. 2003-11-06 US disclosed
US-20030203329-A1 Silver halide photosensitive material FUJI PHOTO FILM CO., LTD. 2003-10-30 US disclosed
US-20030194638-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2003-10-16 US disclosed
EP-1300726-A1 Photothermographic material comprising fragmentable electron donor FUJI PHOTO FILM CO., LTD. (JP) 2003-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050032007-A1 Silver halide emulsion and method of preparing the same TYR, GLO1, GYPA PHGDH 2033/4885HPGD 1328/4885TSHR 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.