SCHEMBL8727982

SCHEMBL8727982

c1ccc(C(=C(c2ccccc2)N2CCOCC2)N2CCOCC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.59
FAAH O00519 1/20 0.59
NCOA3 Q9Y6Q9 1/20 0.59
PHGDH O43175 1/20 0.58
HPGD P15428 1/20 0.58
TSHR P16473 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.54
GAA P10253 1/20 0.54
KMT2A Q03164 4/20 0.51
CYP2C9 P11712 2/20 0.50
CYP2C19 P33261 2/20 0.50
MEN1 O00255 1/20 0.50
AKR1C3 P42330 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
CASP3 P42574 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholino(Phenyl)Methanethione SCHEMBL9180076 0.85 MGLL (0.79) MGLLFAAHNCOA3PHGDHHPGD
SCHEMBL5342293 0.83 PHGDH (0.58) MGLLFAAHNCOA3PHGDHHPGD
SCHEMBL946143 0.79 HPGD (0.86) PHGDHHPGDTSHRSMN1; SMN2GAA
SCHEMBL5949372 0.79 PHGDH (0.54) MGLLFAAHNCOA3PHGDHHPGD
SCHEMBL30449295 0.78 HPGD (0.83) PHGDHHPGDTSHRSMN1; SMN2GAA
Ammonia Solution, Strong SCHEMBL6028542 0.78 HPGD (0.83) PHGDHHPGDTSHRSMN1; SMN2GAA
SCHEMBL10339781 0.77 FAAH (0.46) MGLLFAAHNCOA3PHGDHHPGD
SCHEMBL15540890 0.77 SMN1; SMN2 (0.49) MGLLFAAHNCOA3PHGDHHPGD
SCHEMBL15540893 0.77 SMN1; SMN2 (0.49) MGLLFAAHNCOA3PHGDHHPGD
SCHEMBL8992021 0.76 PHGDH (0.51) MGLLFAAHNCOA3PHGDHHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2767581-B1 METHOD OF LAUNDERING A FABRIC PROCTER & GAMBLE (US) 2020-10-21 EP disclosed
US-10717948-B2 Method of laundering a fabric THE PROCTER & GAMBLE COMPANY (US) 2020-07-21 US disclosed
WO-2014130508-A1 METHOD OF LAUNDERING A FABRIC THE PROCTER & GAMBLE COMPANY (US) 2014-08-28 WO disclosed
WO-2014130509-A1 METHOD OF LAUNDERING A FABRIC THE PROCTER & GAMBLE COMPANY (US) 2014-08-28 WO disclosed
US-20140230157-A1 METHOD OF LAUNDERING A FABRIC THE PROCTER & GAMBLE COMPANY (US) 2014-08-21 US disclosed
US-20140230155-A1 METHOD OF LAUNDERING A FABRIC THE PROCTER & GAMBLE COMPANY (US) 2014-08-21 US disclosed
EP-2767581-A1 METHOD OF LAUNDERING A FABRIC The Procter & Gamble Company (US) 2014-08-20 EP disclosed
EP-2767582-A1 Method of laundering a fabric The Procter and Gamble Company (US) 2014-08-20 EP disclosed
WO-1998021521-A1 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-22 WO disclosed
WO-1995005341-A2 OXIDISING BLEACH ALBRIGHT & WILSON UK LIMITED (GB) 1995-02-23 WO disclosed