SCHEMBL5342403

SCHEMBL5342403

CC1(c2ccccc2)CC(C(=O)O)C(C)(c2ccccc2)N1[O]

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 2/20 0.38
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 4/20 0.34
MEN1 O00255 2/20 0.34
BACE1 P56817 1/20 0.34
MAPT P10636 1/20 0.34
CHRM1 P11229 1/20 0.34
ELOVL1 Q9BW60 1/20 0.34
HSD11B1 P28845 1/20 0.33
HTT P42858 1/20 0.33
MAOB P27338 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3896877 0.84 CCR2 (0.38) CCR2ALDH1A1KMT2AMEN1BACE1
SCHEMBL5343075 0.80 APLNR (0.44) CCR2KMT2AMEN1BACE1MAPT
SCHEMBL5343015 0.76 ALDH1A1 (0.39) CCR2ALDH1A1KMT2AMEN1BACE1
SCHEMBL21447253 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT
SCHEMBL23375794 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT
SCHEMBL23375803 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT
SCHEMBL23356985 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT
SCHEMBL21438851 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT
SCHEMBL21447252 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT
SCHEMBL23375795 0.72 LMNA (0.49) CCR2ALDH1A1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7265166-B2 Aqueous polymer composition ROHM AND HAAS COMPANY (US) 2007-09-04 US disclosed
US-6930141-B2 Antisoilants; wear resistance; acrylated polymer ROHM AND HAAS COMPANY (US) 2005-08-16 US disclosed
US-20050009954-A1 Aqueous polymer composition ROHM AND HAAS COMPANY 2005-01-13 US disclosed
EP-1496091-A1 Aqueous polymer composition ROHM AND HAAS COMPANY (US) 2005-01-12 EP disclosed
US-6713552-B1 EMULSION POLYMER OF SUCH AS ACRYLIC ACID, BUTYL ACRYLATE, 2-ETHYLHEXYL ACRYLATE AND METHYL ACRYLATE FORMED IN PRESENCE OF AN N-OXYL RADICAL ROHM AND HAAS COMPANY 2004-03-30 US disclosed
US-20040010071-A1 Aqueous polymer blend composition ROHM AND HAAS COMPANY 2004-01-15 US disclosed
EP-1352924-A1 Aqueous polymer blend composition ROHM AND HAAS COMPANY (US) 2003-10-15 EP disclosed
EP-1078935-A1 Pressure sensitive adhesive with improved peel strength and tack ROHM AND HAAS COMPANY (US) 2001-02-28 EP disclosed