Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 11/20 | 0.66 |
| ▸ | HTR6 | P50406 | 4/20 | 0.66 |
| ▸ | HTR1A | P08908 | 4/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.66 |
| ▸ | HTR5A | P47898 | 2/20 | 0.66 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723457 | 0.81 | HTR7 (0.51) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL3759275 | 0.81 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL30022433 | 0.81 | HTR7 (1.00) | HTR7HTR6HTR1AHTR2AHTR5A | |
| Hydrochloric Acid SCHEMBL1673713 | 0.79 | HTR7 (0.96) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL6842022 | 0.77 | BCAT2 (0.63) | CYP1A2TSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL379430 | 0.77 | HTR6 (0.51) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL29501947 | 0.76 | NPC1 (0.45) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL27540934 | 0.76 | HTR7 (0.45) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL30556675 | 0.76 | HTR6 (0.58) | HTR7HTR6HTR1AHTR2AHTR5A | |
| SCHEMBL28713189 | 0.76 | NPC1 (0.51) | HTR7HTR6HTR1AHTR2AHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077457-A9 | TREATMENT OF EQUINE LAMINITIS WITH 5-HT1B/ 1D ANTAGONISTS | ROYAL VETERINARY COLLEGE (GB) | 2007-10-18 | — | — | WO | disclosed |