Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5343688 | 0.99 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM3OPRM1 | |
| SCHEMBL5347702 | 0.91 | HSD11B1 (0.35) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL5346025 | 0.90 | HSD11B1 (0.35) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL5339945 | 0.89 | CYP2D6 (0.36) | CHRM2CHRM1OPRM1ALDH1A1 | |
| SCHEMBL5343241 | 0.79 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM3OPRM1 | |
| Hydrochloric Acid SCHEMBL5343678 | 0.79 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM3OPRM1 | |
| SCHEMBL2472859 | 0.75 | SLC18A3 (0.41) | LMNATSHRHTTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5344037 | 0.73 | MAPT (0.34) | KDM4E | |
| SCHEMBL5351949 | 0.72 | LMNA (0.35) | LMNAALDH1A1 | |
| SCHEMBL5347690 | 0.70 | HSD11B1 (0.36) | CHRM2CHRM1HSD11B1OGAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208495-B2 | Benzo-fused 5-membered hetrocycle compounds, process for preparation of the same, and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-04-24 | — | — | US | claimed |