Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.50 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
| ▸ | AKT2 | P31751 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338026 | 0.86 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2ASLC6A7MEN1 | |
| SCHEMBL5345220 | 0.85 | KDM4E (0.59) | ALDH1A1KMT2ASLC2A1RAB9AMAPT | |
| SCHEMBL5341068 | 0.85 | SLC2A2 (0.52) | SLC2A1 | |
| SCHEMBL5318714 | 0.85 | POLB (0.56) | LMNAALDH1A1KMT2APOLBSLC2A1 | |
| SCHEMBL5322233 | 0.85 | CNR1 (0.58) | KMT2AMEN1SLC2A1F2RL1AKT1 | |
| SCHEMBL5337926 | 0.85 | CNR1 (0.58) | KMT2AMEN1SLC2A1F2RL1AKT1 | |
| SCHEMBL5342501 | 0.83 | CCNC (0.45) | ALDH1A1SLC2A1AKT1AKT2SMN1; SMN2 | |
| SCHEMBL5339197 | 0.82 | CASP1 (0.49) | LMNAALDH1A1KMT2AMEN1SLC2A1 | |
| SCHEMBL5319613 | 0.82 | SLC2A1 (0.52) | LMNAALDH1A1SLC2A1MAPTSMN1; SMN2 | |
| SCHEMBL5341500 | 0.82 | KMT2A (0.60) | KMT2APOLBSLC2A1F2RL1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |