Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342530 | 1.00 | GLA (0.40) | GLANPC1RAB9AMAPTGAA | |
| SCHEMBL14369909 | 0.82 | ALDH1A1 (0.41) | NPC1RAB9AMAPTALDH1A1GFER | |
| SCHEMBL14369908 | 0.82 | ALDH1A1 (0.41) | NPC1RAB9AMAPTALDH1A1GFER | |
| SCHEMBL5528790 | 0.80 | ALDH1A1 (0.40) | RAB9AMAPTALDH1A1GFERHPGD | |
| SCHEMBL5344632 | 0.75 | BACE1 (0.35) | ALDH1A1GFER | |
| SCHEMBL5337630 | 0.75 | BACE1 (0.35) | ALDH1A1GFER | |
| SCHEMBL5337930 | 0.75 | NPC1 (0.36) | GLANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL5528287 | 0.74 | ALDH1A1 (0.44) | NPC1RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL14297450 | 0.74 | CHRNA7 (0.46) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14399277 | 0.74 | TLR4 (0.44) | NPC1RAB9AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279601-B2 | Optically active α-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1661885-A1 | OPTICALLY ACTIVE ALPHA-AMINOOXYKETONE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Tokyo University of Science (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | ALDH7A1, ASPH, KMO | GLA 986/4885NPC1 3652/4885RAB9A 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.