Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 17/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 16/20 | 0.45 |
| ▸ | TSHR | P16473 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352140 | 0.92 | CYP3A4 (0.35) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5349603 | 0.87 | TACR1 (0.36) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5341436 | 0.86 | KMT2A (0.35) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL7106979 | 0.85 | CYP3A4 (0.36) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5343252 | 0.84 | LMNA (0.35) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5341696 | 0.84 | CYP3A4 (0.32) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5345375 | 0.84 | KDM1A (0.34) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5338564 | 0.84 | TACR1 (0.32) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5348582 | 0.83 | ALDH1A1 (0.38) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL5353310 | 0.83 | HTT (0.33) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624306-B2 | Stabilizer for addition polymer | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | claimed |
| US-20030166939-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | NESVADBA PETER (CH) | 2003-09-04 | — | — | US | claimed |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | claimed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-20050143539-A1 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | NESVADBA PETER (CH) | 2005-06-30 | — | — | US | disclosed |
| US-6624306-B2 | Stabilizer for addition polymer | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166939-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | CYP3A4 1111/4885CYP2C9 1680/4885CYP2C19 2112/4885 |
| US-20050143539-A1 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | CYP3A4 1111/4885CYP2C9 1680/4885CYP2C19 2112/4885 |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | CYP3A4 1111/4885CYP2C9 1680/4885CYP2C19 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.