Pyridoxine

Pyridoxine

SCHEMBL5345135

Cc1ncc(CO)c(CO)c1O.O=C(O)CC(O)(CC(=O)OO)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 4/20 0.55
HPGD P15428 3/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 4/20 0.45
GAA P10253 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
AOX1 Q06278 1/20 0.39
SLC13A5 Q86YT5 4/20 0.38
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
SLC13A2 Q13183 1/20 0.38
SLC13A3 Q8WWT9 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
PDXK O00764 2/20 0.36
HDAC1 Q13547 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL5345353 0.92 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL5346680 0.80 KDM4E (0.80) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL1962868 0.76 KDM4E (0.56) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL31514964 0.76 KDM4E (0.77) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL23647341 0.76 KDM4E (0.83) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL15486045 0.74 KDM4E (0.80) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL30877002 0.74 HPGD (1.00) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL30267871 0.74 HPGD (1.00) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL3506 0.74 HPGD (1.00) ALDH1A1KDM4EHPGDHSD17B10LMNA
Pyridoxine SCHEMBL28806638 0.73 KDM4E (0.73) ALDH1A1KDM4EHPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040228884-A1 Ion-pair delivery system for cosmetic and pharmaceutical compositions GUPTA SHYAM K (US) 2004-11-18 US claimed
US-20040156873-A1 Topically Bioavailable Acne and Rosacea Treatment Compositions GUPTA SHYAM K (US) 2004-08-12 US claimed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US claimed
US-7179477-B2 Cosmetic dermabrasion treatment system GUPTA SHYAM K 2007-02-20 US disclosed
US-20060147508-A1 Concurrent Enhancement of Skin Penetration of Organic Base Active Agents and Organic Hydroxy Acid Active Agents as Their Ion-Pair Complexes BIODERM RESEARCH (US) 2006-07-06 US disclosed
WO-2006023710-A2 COSMETIC OR PHARMACEUTICAL COMPOSITION FOR SKIN CARE INFINITY2 HEALTH SCIENCES, INC. (US) 2006-03-02 WO disclosed
US-20060039887-A1 Cosmetic or pharmaceutical composition for skin care INFINITY2 HEALTH SCIENCES, INC. 2006-02-23 US disclosed
US-20050037038-A1 Cosmetic Dermabrasion Treatment System GUPTA SHYAM K (US) 2005-02-17 US disclosed
US-20040228884-A1 Ion-pair delivery system for cosmetic and pharmaceutical compositions GUPTA SHYAM K (US) 2004-11-18 US disclosed
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions GUPTA SHYAM K (US) 2004-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040092482-A1 Hydroxy acids based delivery systems for skin resurfacing and anti-aging compositions CUTA, HIRA, HARS1 ALDH1A1 1928/4885KDM4E 2354/4885HPGD 2576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.