Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569464 | 0.82 | MAPT (0.44) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL863877 | 0.80 | MAPT (0.42) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11653130 | 0.74 | HPGD (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16594998 | 0.73 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL2574845 | 0.72 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6470812 | 0.71 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8069981 | 0.70 | MAPT (0.38) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL23494391 | 0.70 | TSHR (0.39) | ALDH1A1 | |
| SCHEMBL305727 | 0.70 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1493637 | 0.70 | HPGD (0.42) | ALDH1A1KDM4EKMT2AHTTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007083154-A1 | AMPHIPATHIC POLYMER CONJUGATES FOR SOLUBILISATION OF HYDROPHOBIC PROTEINS | BABRAHAM BIOSCIENCE TECHNOLOGIES LIMITED (GB) | 2007-07-26 | — | — | WO | disclosed |