Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569464 | 0.85 | MAPT (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL5345228 | 0.80 | MAPT (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL6263247 | 0.79 | MAPT (0.42) | MAPTALDH1A1KLK7SMN1; SMN2HTT | |
| SCHEMBL28199415 | 0.79 | CTSK (0.51) | ALDH1A1ELANERAB9APKM | |
| SCHEMBL29061553 | 0.78 | MMP12 (0.48) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL22417560 | 0.77 | MTNR1A (0.47) | — | |
| SCHEMBL11653130 | 0.76 | HPGD (0.41) | MAPTALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL16594998 | 0.75 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| Dimethylamine SCHEMBL27868377 | 0.75 | LMNA (0.48) | MAPTALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL440616 | 0.75 | TSHR (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077977-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N,N-SUBSTITUTED AMINO ALCOHOLS | BASF SE (DE) | 2012-03-29 | — | — | US | disclosed |
| US-20100286331-A1 | TWO OR MORE-COMPONENT SYSTEM CURED BY A REDOX INITIATOR SYSTEM WITH CONTROLLABLE WORKING LIFE, AND THE USE THEREOF | EVONIK ROEHM GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100210784-A1 | EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS | EVONIK RÖHM GMBH (DE) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077977-A1 | PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N,N-SUBSTITUTED AMINO ALCOHOLS | ADH5, ADH1A, METTL14 | MAPT 4143/4885ALDH1A1 303/4885KDM4E 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.