Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594998 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2MTNR1A | |
| SCHEMBL863877 | 0.85 | MAPT (0.42) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL8069981 | 0.83 | MAPT (0.38) | MAPTALDH1A1KDM4ESMN1; SMN2MTNR1A | |
| SCHEMBL5345228 | 0.82 | MAPT (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL11653130 | 0.81 | HPGD (0.41) | MAPTALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL3681972 | 0.79 | LMNA (0.47) | ALDH1A1LMNACYP1A2ELANERAB9A | |
| SCHEMBL8203974 | 0.79 | LMNA (0.53) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL305727 | 0.78 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL9189006 | 0.76 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL17891305 | 0.76 | HPGD (0.41) | MAPTALDH1A1SMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |